First Author | Lee J | Year | 2000 |
Journal | Biochim Biophys Acta | Volume | 1491 |
Issue | 1-3 | Pages | 355-63 |
PubMed ID | 10760603 | Mgi Jnum | J:61720 |
Mgi Id | MGI:1355460 | Doi | 10.1016/s0167-4781(00)00047-6 |
Citation | Lee J, et al. (2000) Characterization of JDP genes, an evolutionarily conserved J domain-only protein family, from human and moths. Biochim Biophys Acta 1491(1-3):355-63 |
abstractText | We characterized evolutionarily conserved J domain containing protein (JDP) genes from human, Bombyx mori, and Manduca sexta. Each of the JDP proteins contains a J domain at its N-terminus and a highly conserved C-terminal domain. Southern blot analysis revealed that the human JDP1 gene is present as a single copy in the human genome. Expression was higher in brain, heart, and testis than in kidney or stomach. Human JDP1 was mapped in silico to chromosome 10q21.1, which exhibits a conserved synteny with the central region of mouse chromosome 10. Drosophila jdp is located at 99F4-99F11 on the right arm of the third chromosome. |