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Protein Domain : Wings apart-like protein, C-terminal

Primary Identifier  IPR022771 Type  Domain
Short Name  WAPL_C
description  This entry represents the conserved region of D. melanogaster wings apart-like protein, WAPL. It is involved in the regulation of heterochromatin structure []. hWAPL (), the human homologue, is found to play a role in the development of cervical carcinogenesis, and is thought to have similar functions to Drosophila wapl protein []. Malfunction of the hWAPL pathway is thought to activate an apoptotic pathway that consequently leads to cell death [].The WAPL-like proteins can be found in metazoa, fungi and plants.

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4 Protein Domain Regions