Primary Identifier | IPR022771 | Type | Domain |
Short Name | WAPL_C |
description | This entry represents the conserved region of D. melanogaster wings apart-like protein, WAPL. It is involved in the regulation of heterochromatin structure []. hWAPL (), the human homologue, is found to play a role in the development of cervical carcinogenesis, and is thought to have similar functions to Drosophila wapl protein []. Malfunction of the hWAPL pathway is thought to activate an apoptotic pathway that consequently leads to cell death [].The WAPL-like proteins can be found in metazoa, fungi and plants. |