| Primary Identifier | IPR034601 | Type | Family |
| Short Name | LAMTOR4 |
| description | Lamtor4 is a component of the Ragulator complex, a complex that functions as a guanine nucleotide exchange factor for the Rag GTPases that signal amino acid levels to mTORC1. The mTOR Complex 1 (mTORC1) pathway regulates cell growth in response to numerous cues. Lamtor4 is required for mTORC1 activation by amino acids []. The Rag-Ragulator complex also has functions independent of mTOR signaling; RagA and Lamtor4 are essential regulators of lysosomes in microglia []. |
