Primary Identifier | MGI:2386285 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ivl |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The entire coding region of the endogenous gene was replaced with a neomycin selection cassette via homologous recombination. Northern blot analysis of total RNA isolated from skin samples showed an absence of transcript in homozygous mutant mice. A lack of protein was confirmed by both Western blot analysis and in situ hybridization. |