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Protein Coding Gene : Dlgap3 DLG associated protein 3
Primary Identifier  MGI:3039563 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  242667
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables amyloid-beta binding activity. Involved in modification of postsynaptic structure and modulation of chemical synaptic transmission. Located in synapse. Is active in several cellular components, including cholinergic synapse; glutamatergic synapse; and neuromuscular junction. Is expressed in corpus striatum. Orthologous to human DLGAP3 (DLG associated protein 3).
PHENOTYPE: Mice homozygous for a null allele exhibit skin lesions associated with excessive grooming, increased anxiety-related behaviors, altered synaptic transmission and abnormal sleep patterns. [provided by MGI curators]
  • synonyms:
  • Prpl8,
  • BC058433,
  • Dlgap3,
  • SAP90/PSD 95 associated protein 3,
  • cDNA sequence BC058433,
  • DAP3,
  • DLG associated protein 3,
  • Sapap3,
  • prion protein ligand 8,
  • PSD-95/SAP90-binding protein 3,
  • MGI:892992
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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