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Allele : Crb1<em2Jnk> crumbs family member 1, photoreceptor morphogenesis associated; endonuclease-mediated mutation 2, Jeremy N Kay

Primary Identifier  MGI:6467932 Allele Type  Endonuclease-mediated
Attribute String  Modified isoform(s) Gene  Crb1
Strain of Origin  (C57BL/6J x SJL)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a 1652 bp deletion from chr1:139,254,836-139,256,488, plus a deletion of two additional cytosines, deleting the entire first exon of the B isoform (Crb1-B) and the promoter region. This abolishes the B isoform while preserving other isoforms including the A isoform.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Crb1<delB>,
  • Crb1<delB>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele