Primary Identifier | MGI:6467932 | Allele Type | Endonuclease-mediated |
Attribute String | Modified isoform(s) | Gene | Crb1 |
Strain of Origin | (C57BL/6J x SJL)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a 1652 bp deletion from chr1:139,254,836-139,256,488, plus a deletion of two additional cytosines, deleting the entire first exon of the B isoform (Crb1-B) and the promoter region. This abolishes the B isoform while preserving other isoforms including the A isoform. |