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Allele : Hand1<tm3Abfi> heart and neural crest derivatives expressed 1; targeted mutation 3, Anthony B Firulli

Primary Identifier  MGI:5604130 Allele Type  Targeted
Attribute String  Conditional ready Gene  Hand1
Transmission  Germline Strain of Origin  129S/SvEv
Is Recombinase  false Is Wild Type  false
molecularNote  Residues T107 and S109 were replaced with alanines. A Stop-flox cassette containing a neomycin resistance gene was also inserted downstream of the Hand1 transcriptional start site, but upstream of the Hand1-initiating methionine. Cre-excision of the stop cassette results in expression of the mutant.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • PO4-,
  • PO4-,
  • Hand1<stopfloxHand1T107;S109A>,
  • Hand1<stopfloxHand1T107;S109A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele