Primary Identifier | MGI:5762965 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tgfb1i1 |
Transmission | Germline | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 1'. A floxed neomycin resistance cassette was inserted downstream of exon 10. Cre-mediated recombination removed exon 1' through exon 10. Western blot analysis confirmed the absence of protein expression in lungs and aortic vascular smooth muscle cells. |