Primary Identifier | IPR039983 | Type | Family |
Short Name | CYP46A1 |
description | Cholesterol 24-hydroxylase (CYP46A1) is the neuronal-specific and rate-limiting enzyme for cholesterol conversion to 24S-hydroxycholesterol (24S-OHC) [, ]. It has a neuroprotective effect in Huntington's disease, a genetic disease that leads to many cellular dysfunctions, including abnormalities in cholesterol metabolism [, ]. |