Primary Identifier | IPR044554 | Type | Family |
Short Name | APC2-like |
description | The anaphase-promoting complex (APC) or cyclosome is a multi-subunit E3 protein ubiquitin ligase that regulates important events in mitosis, such as the initiation of anaphase and exit from telophase. The APC, in conjunction with other enzymes, assembles multi-ubiquitin chains on a variety of regulatory proteins, thereby targeting them for proteolysis by the 26S proteasome [].This entry represents APC subunit 2, which is a distant member of the cullin protein family that functions as a scaffold in SCF assembly []. |