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Protein Coding Gene : Strip2 striatin interacting protein 2

Primary Identifier  MGI:2444363 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  320609
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to be involved in cell migration; cytoskeleton organization; and regulation of cell shape. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in brain and cochlea epithelium. Orthologous to human STRIP2 (striatin interacting protein 2).
PHENOTYPE: Homozygous knockout affects cardiac muscle contractility under basal conditions and worsening pulmonary congestion and cardiac phenotypes (muscle contractility reduction, hypertrophy, fibrosis) under pressure overload. [provided by MGI curators]
  • synonyms:
  • striatin interacting protein 2,
  • RIKEN cDNA D330017J20 gene,
  • mKIAA1170,
  • Myoscape,
  • Fam40b,
  • family with sequence similarity 40, member B,
  • Strip2,
  • D330017J20Rik

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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