Primary Identifier | MGI:2444363 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 320609 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to be involved in cell migration; cytoskeleton organization; and regulation of cell shape. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in brain and cochlea epithelium. Orthologous to human STRIP2 (striatin interacting protein 2). PHENOTYPE: Homozygous knockout affects cardiac muscle contractility under basal conditions and worsening pulmonary congestion and cardiac phenotypes (muscle contractility reduction, hypertrophy, fibrosis) under pressure overload. [provided by MGI curators] |