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Publication : cDNA cloning and localization of the mouse leukosialin gene (Ly48) to chromosome 7.

First Author  Baecher CM Year  1990
Journal  Immunogenetics Volume  31
Issue  5-6 Pages  307-14
PubMed ID  1973410 Mgi Jnum  J:10632
Mgi Id  MGI:59080 Doi  10.1007/BF02115004
Citation  Baecher CM, et al. (1990) cDNA cloning and localization of the mouse leukosialin gene (Ly48) to chromosome 7. Immunogenetics 31(5-6):307-14
abstractText  Mouse leukosialin, previously known as the 3E8 antigen, is expressed primarily on cells of the hematopoietic and lymphoid lineages and is shown to be the mouse homologue to the human leukosialin/sialophorin and rat W3/13 molecules. A partial leukosialin cDNA clone was isolated via cross-species hybridization with a portion of a human leukosialin cDNA. This mouse cDNA clone was used to demonstrate that the leukosialin isoforms are encoded by a single mRNA species of approximately 4.2 kilobases (kb) and that the leukosialin gene is located on chromosome 7. Based on these results, mouse leukosialin is given the designation Ly48.
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