| Primary Identifier | MGI:1336159 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 17330 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables inositol phosphate phosphatase activity. Is active in endoplasmic reticulum lumen and plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 16 and thyroid gland papillary carcinoma. Orthologous to human MINPP1 (multiple inositol-polyphosphate phosphatase 1). PHENOTYPE: Mice homozygous for a targeted null mutation exhibit no discernable phenotype. Another null allele shows a 10% decrease in brain weight due to reduced cortical thickness and decreased intracellular free calcium levels in E14.5 neural progenitors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
