Primary Identifier | MGI:3758645 | Allele Type | Chemically induced (ENU) |
Gene | Pgm3 | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A T to A transversion was induced by ENU mutagenisis in the fourth intron 14 bp upstream of exon 5. A complimentation assay was performed to determine the gene affected. While a transcript is detectable by RT-PCR the resulting protein has less than 1% of wild-type enzymatic activity in the testes, spleen, pancreas and heart. |