| Primary Identifier | MGI:1916931 | Organism | mouse, laboratory |
| Chromosome | 11 | Mgi Type | polymorphic pseudogene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in several processes, including G0 to G1 transition; G1/S transition of mitotic cell cycle; and negative regulation of Notch signaling pathway. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including chondrocranium; heart; hindbrain roof; lung; and nasal cavity. Orthologous to human CDK3 (cyclin dependent kinase 3). PHENOTYPE: Mice homozygous for a spontaneous null mutation do not exhibit any overt abnormalities. [provided by MGI curators] |
| specificity | A point mutation that converts a highly conserved tyrptophan (Trp-187) to a premature termination codon in the Cdk3 locus is found in several mouse strains: C57BL/6J, BALB/c,129Sv and FVB/NJ. The Cdk3 locus in CAST/Ei and CASA/Rk do not carry this mutation. |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
