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Comment :

Type  MGI:General Description  mice treated with 3 injections of pIpC every second day at 4 to 10 weeks of age develop diffuse mastocytosis by 13 - 38 weeks of age pIpC treated mice display a variable increase in cutaneous mast cell numbers in some pIpC treated mice accumulations of mast cells are seen in the lymph nodes, spleen, liver and/or stomach mice not treated with pIpC develop phenotypes similar to those in pIpC injected mice