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Protein Domain : Pestivirus envelope glycoprotein E2, domain D

Primary Identifier  IPR042311 Type  Homologous_superfamily
Short Name  Pestivirus_E2_D
description  Pestiviruses have an outer lipid envelope bearing two glycoproteins, E1 and E2, required for cell entry. E2 is an elongated molecule which consists of four domains (DA, DB, DC, DD), arranged linearly from N to C terminus. Domains DA and DB are the most distal from the viral membrane and are likely to be the most exposed on the virus surface. Both domains possess Ig-like folds, consistent with a cell-receptor binding function [].This superfamily represents the domain D (DD) found at the C terminus of the Pestivirus envelope glycoprotein E2.

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