| Primary Identifier | MGI:1314647 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 11832 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable glycerol channel activity; urea channel activity; and water channel activity. Acts upstream of or within glycerol transmembrane transport and renal water absorption. Located in plasma membrane. Colocalizes with lipid droplet. Is expressed in early conceptus; genitourinary system; inner ear; and liver. Orthologous to several human genes including AQP7 (aquaporin 7). PHENOTYPE: Homozygous null mice for one allele show decreased circulating glycerol levels and fasting hypoglycemia. Other mutant alleles show increased gonadal fat pad mass and adipocyte hypertrophy or increased urine glucose and impaired water permeability in the kidney, but have normal serum glycerol. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
