| Primary Identifier | MGI:7264934 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Mirc33 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A 0.6kb region in length including Mir29a and Mir29b-1 pre-microRNAs was removed in this strain. Real-time PCR analysis demonstrated absence of mature Mir29a RNA in various tissues of homozygous mutant mice. Precursor RNA levels of pre-Mir29a or pre-Mir29a were reduced in heterozygous mice and nearly undetectable in homozygous mutant mice. |
