Primary Identifier | MGI:2682305 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 233532 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable histone binding activity and histone octamer slider activity. Predicted to be involved in several processes, including nucleosome assembly; positive regulation of viral transcription; and regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be part of RSF complex. Is expressed in several structures, including ear; genitourinary system; and nervous system. Orthologous to human RSF1 (remodeling and spacing factor 1). PHENOTYPE: Mice homozygous for a conditional allele activated in neurons exhibit increased susceptibility to etoposide-induced neuron apoptosis with failure to repair double-strand breaks. [provided by MGI curators] |