| Primary Identifier | MGI:98937 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 22363 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Acts upstream of or within several processes, including B cell homeostasis; B cell proliferation; and regulation of cell size. Predicted to be active in extracellular space. Is expressed in bone marrow; liver; and spleen. Orthologous to human VPREB1 (V-set pre-B cell surrogate light chain 1). PHENOTYPE: Mice homozygous for null mutations at both Vpreb1 and Vpreb2 show impaired B-cell development. Fewer small pre-BII and immature B- cells are in bone marrow and numbers of B-cells in spleen and peritoneum are reduced. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
