| Type | MGI:General | Description | mice show an increased hypertrophic response to mechanical overload in skeletal muscle with a higher level of increase in both maximal force and fatigue resistance relative to controls increased muscle remodeling capacity is characterized by muscle fibers switching to a more oxidative phenotype, reduced myostatin (Mstn) and atrogin (Fbxo32) mRNA levels, increased follistatin (Fst) mRNA levels, and higher levels of phosphorylated forms of signaling molecules implicated in muscle hypertrophy at 7 days after overload |
