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Protein Coding Gene : Fxr2 FMR1 autosomal homolog 2

Primary Identifier  MGI:1346074 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  23879
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable mRNA 3'-UTR binding activity; protein dimerization activity; and translation regulator activity. Involved in dentate gyrus development and mRNA destabilization. Located in dendrite and ribosome. Is active in cytoplasm; glutamatergic synapse; and postsynapse. Is expressed in central nervous system; female reproductive system; peripheral nervous system; sensory organ; and skin. Orthologous to human FXR2 (FMR1 autosomal homolog 2).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit hyperactivity, impaired Morris water task performance, and reductions in prepulse inhibition, contextual conditioned fear, and sensitivity to heat stimulus. [provided by MGI curators]
  • synonyms:
  • Fxr2,
  • FMR1 autosomal homolog 2,
  • fragile X mental retardation gene 2, autosomal homolog,
  • Fxr2h

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For