| Primary Identifier | MGI:2658730 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hyal1 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| description | MMRRC states the founder genetic background as 129P2/OlaHsd, however this has not been confirmed. |
| molecularNote | A Neo cassette was inserted into exon 2, replacing nucleotides 6487518-6488270 of GenBank NT_039477.6. This replacement resulted in the deletion of nearly half of the coding region, 753 bp, and included a DWE amino acid sequence. Western blot analysis confirmed absence of protein and HA zymography of serum showed no detectable hyaluronidase activity in homozygotes. |
