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Protein Coding Gene : Puf60 poly-U binding splicing factor 60

Primary Identifier  MGI:1915209 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  67959
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable identical protein binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome; mRNA splice site recognition; and regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing; apoptotic process; and mRNA processing. Predicted to be located in cell junction and nucleoplasm. Predicted to be part of ribonucleoprotein complex. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Orthologous to human PUF60 (poly(U) binding splicing factor 60).
PHENOTYPE: Mice homozygous for a null allele die prior to E4.5. Mice heterozygous for a null allele exhibit with increased organ or bone marrow invasion with poor prognosis in the presence of a Trp53 null allele. [provided by MGI curators]
  • synonyms:
  • poly-U binding splicing factor 60,
  • RIKEN cDNA 2810454F19 gene,
  • 2410104I19Rik,
  • Puf60,
  • 2810454F19Rik,
  • RIKEN cDNA 2410104I19 gene,
  • MGI:1920052

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

5 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For