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Allele : Tg(MMTV-Akt1*T308D*S473D)7Mul transgene insertion 7, William J Muller

Primary Identifier  MGI:3794053 Allele Type  Transgenic
Attribute String  Constitutively active, Inserted expressed sequence Gene  Tg(MMTV-Akt1*T308D*S473D)7Mul
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene contains a constitutively active mouse Akt1, in which critical residues (T308D/S473D) for activation of Akt1 are replaced by negatively charged amino acids, under the control of the mouse mammary tumor virus LTR. Mammary glands express significant levels of the transgene.
  • mutations:
  • Insertion
  • synonyms:
  • Akt7,
  • Akt7,
  • MMTV-Akt1-DD,
  • MMTV/AktDD-7,
  • MMTV/AktDD-7,
  • MMTV-Akt1-DD
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele