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Allele : mt-Tk<m1> mitochondrially encoded tRNA lysine; mutation 1

Primary Identifier  MGI:5606283 Allele Type  Spontaneous
Gene  mt-Tk Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Mitochondria with a ChrM:7731G>A mutation in the mitochondrially encoded lysine tRNA were identified in P29 cells. Cybrids created in B82 cells lacking mitochondrial DNA and then transferred to TT2-F ES cells were introduced into 8-cell stage embryos of ICR mice. Cybrids were estimated to have 70% mutant DNA.
  • mutations:
  • Single point mutation
  • synonyms:
  • tRNA<Lys7731>,
  • tRNA<Lys7731>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele