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Allele : Kit<tm1Shta> KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1, Shonzo Hirota

Primary Identifier  MGI:3773048 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Kit
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette and an exon 17 carrying a nucleotide substitution that results in an amino acid substitution of tyrosine for aspartic acid at position 818 (D818Y) was knocked into the open reading frame. The neo cassette was subsequently removed by germ-line, cre-mediated recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • KIT-Asp818Tyr,
  • KIT-Asp818Tyr
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele