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Protein Coding Gene : Ccar2 cell cycle activator and apoptosis regulator 2

Primary Identifier  MGI:2444228 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  219158
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables enzyme inhibitor activity. Involved in regulation of circadian rhythm. Predicted to be located in mitochondrial matrix; nucleoplasm; and spindle. Predicted to be part of DBIRD complex and chromatin. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system and retina. Orthologous to human CCAR2 (cell cycle and apoptosis regulator 2).
PHENOTYPE: Homozygous null mice on a high fat diet are resistant to hepatic steatosis and associated liver inflammation. [provided by MGI curators]
  • synonyms:
  • Ccar2,
  • Dbc1,
  • 2610301G19Rik,
  • cell cycle activator and apoptosis regulator 2,
  • mKIAA1967,
  • RIKEN cDNA 2610301G19 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For