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Protein Domain : Tectonin beta-propeller repeat-containing protein 2

Primary Identifier  IPR029772 Type  Family
Short Name  TECPR2
description  Tectonin β-propeller repeat-containing protein 2 probably plays a role as positive regulator of autophagy []. Mutations in TECPR2 gene cause Spastic paraplegia 49, autosomal recessive (SPG49), which is a form of spastic paraplegia, a neurodegenerative disorder characterised by a slow, gradual, progressive weakness and spasticity of the lower limb [].This entry also includes WD repeat-containing protein CG11141 from Drosophila melanogaster. The function of CG11141 is not clear.

0 Child Features

0 Parent Features

5 Protein Domain Regions