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Publication : Expression of a large family of POU-domain regulatory genes in mammalian brain development.

First Author  He X Year  1989
Journal  Nature Volume  340
Issue  6228 Pages  35-41
PubMed ID  2739723 Mgi Jnum  J:9856
Mgi Id  MGI:58313 Doi  10.1038/340035a0
Citation  He X, et al. (1989) Expression of a large family of POU-domain regulatory genes in mammalian brain development [published erratum appears in Nature 1989 Aug 24;340(6235):662]. Nature 340(6228):35-41
abstractText  A novel region referred to as the POU-domain is present in two tissue-specific transcription factors, Pit-1 and Oct-2, that activate expression of genes specifying pituitary and lymphocyte phenotypes. We report the identification of multiple new members of a large family of POU-domain genes expressed in adult brain, and document that all the known mammalian POU-domain genes, including Pit-1 and Oct-2, are expressed widely in the developing nervous system.
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