First Author | He X | Year | 1989 |
Journal | Nature | Volume | 340 |
Issue | 6228 | Pages | 35-41 |
PubMed ID | 2739723 | Mgi Jnum | J:9856 |
Mgi Id | MGI:58313 | Doi | 10.1038/340035a0 |
Citation | He X, et al. (1989) Expression of a large family of POU-domain regulatory genes in mammalian brain development [published erratum appears in Nature 1989 Aug 24;340(6235):662]. Nature 340(6228):35-41 |
abstractText | A novel region referred to as the POU-domain is present in two tissue-specific transcription factors, Pit-1 and Oct-2, that activate expression of genes specifying pituitary and lymphocyte phenotypes. We report the identification of multiple new members of a large family of POU-domain genes expressed in adult brain, and document that all the known mammalian POU-domain genes, including Pit-1 and Oct-2, are expressed widely in the developing nervous system. |