| Primary Identifier | MGI:96787 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 16878 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables cytokine activity and growth factor activity. Acts upstream of or within several processes, including cell differentiation involved in embryonic placenta development; lung development; and positive regulation of macromolecule biosynthetic process. Located in extracellular space. Is expressed in several structures, including alimentary system; early conceptus; hemolymphoid system; nervous system; and reproductive system. Orthologous to human LIF (LIF interleukin 6 family cytokine). PHENOTYPE: Homozygotes for targeted null mutations have reduced numbers of stem cells in spleen and bone marrow, enhanced inflammatory responses, impaired sensory neuron regrowth, and uterine insufficiency. Heterozygotes show intermediate numbers of stem cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
