Primary Identifier | MGI:2444393 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 208884 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable Ras palmitoyltransferase activity. Predicted to be involved in positive regulation by host of viral process; positive regulation of cGAS/STING signaling pathway; and protein targeting to membrane. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of palmitoyltransferase complex. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in cerebral cortex ventricular layer and cortical plate. Used to study syndromic X-linked intellectual disability Raymond type. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Raymond type. Orthologous to human ZDHHC9 (zinc finger DHHC-type palmitoyltransferase 9). PHENOTYPE: Null males exhibit decreased body weight, hypotonia, decreased anxiety, spatial learning deficits, decreased acoustic startle response and decreased corpus callosum volume. [provided by MGI curators] |