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Allele : Ccdc62<em1Jxia> coiled-coil domain containing 62; endonuclease-mediated mutation 1, Jun Xia

Primary Identifier  MGI:6116688 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ccdc62
Inheritance Mode  Recessive Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Using four sgRNAs and CRISPR/Cas9 technology in C57BL/6 zygotes to delete exon 2, resulted in the creation of four mutant pups (No.7, 10, 22 and 26). Founder number 7 was used to establish a germ line. This allele represents a 146 bp deletion, which removes most of exon 2 and creates a frame shift and premature stop codon.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele