Primary Identifier | MGI:6116688 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Ccdc62 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Using four sgRNAs and CRISPR/Cas9 technology in C57BL/6 zygotes to delete exon 2, resulted in the creation of four mutant pups (No.7, 10, 22 and 26). Founder number 7 was used to establish a germ line. This allele represents a 146 bp deletion, which removes most of exon 2 and creates a frame shift and premature stop codon. |