| Primary Identifier | MGI:1333807 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 19356 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable chromatin binding activity and chromatin-protein adaptor activity. Predicted to contribute to DNA clamp loader activity. Acts upstream of or within DNA damage response. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Rad17 RFC-like complex. Predicted to be active in site of double-strand break. Predicted to colocalize with chromosome, telomeric region. Is expressed in cerebral cortex; embryo; and telencephalon. Orthologous to human RAD17 (RAD17 checkpoint clamp loader component). PHENOTYPE: Homozygous null mice display embryonic lethality with incomplete somite formation, abnormal bracnchial arch, liver, and heart morphology, abnormal neural tube development, and multiple hemorrhages. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
