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Protein Coding Gene : Kcnk6 potassium inwardly-rectifying channel, subfamily K, member 6

Primary Identifier  MGI:1891291 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  52150
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Acts upstream of or within negative regulation of systemic arterial blood pressure and regulation of resting membrane potential. Predicted to be active in plasma membrane. Is expressed in heart; liver left lobe; and liver right lobe. Orthologous to human KCNK6 (potassium two pore domain channel subfamily K member 6).
PHENOTYPE: Male mice homozygous for a knock-out allele exhibit vascular dysfunction and hypertension. [provided by MGI curators]
  • synonyms:
  • D7Ertd764e,
  • MGI:1289340,
  • potassium inwardly-rectifying channel, subfamily K, member 6,
  • Twik2,
  • DNA segment, Chr 7, ERATO Doi 764, expressed,
  • Toss,
  • Kcnk6

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For