| Primary Identifier | MGI:103107 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 14058 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable phospholipid binding activity and serine-type endopeptidase activity. Predicted to be involved in positive regulation of TOR signaling. Predicted to act upstream of or within hemostasis and proteolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including bone; lateral plate mesoderm; liver and biliary system; testis; and yolk sac. Human ortholog(s) of this gene implicated in breast cancer and factor X deficiency. Orthologous to human F10 (coagulation factor X). PHENOTYPE: Most homozygous mice die from fatal bleeding events at embryonic and neonatal stages, with the remaining homozygous mice dying before weaning stages. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
