Primary Identifier | MGI:1856614 | Allele Type | Spontaneous |
Gene | Sobp | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
description | Homozygotes show erratic circling behavior which becomes more pronounced with age. They can swim. They are very active, bobbing up and down and flexing head and trunk ventrally towards the tail. Flexing behavior when suspended by tail is diagnostic at weaning age. jc is not allelic with other circling mutants on Chr 10 (J:13506). |
molecularNote | A 10 bp deletion is found in exon 6 eliminating nucleotides 1346-1355 of the BC059851 coding sequence. This results in the deletion of 48% of the protein. |