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Protein Coding Gene : Cep20 centrosomal protein 20
Primary Identifier  MGI:1913336 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  66086
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable identical protein binding activity. Predicted to be involved in cilium assembly. Predicted to act upstream of or within cell projection organization. Located in ciliary basal body and motile cilium. Is expressed in several structures, including central nervous system; heart; liver; lung; and spleen. Orthologous to human CEP20 (centrosomal protein 20).
PHENOTYPE: Homozygous knock-out results in embryonic growth arrest and lethality around E10.5 to E11.5, impaired left-right pattering with failed body turning and disorganized heart looping, defective angiogenesis, and disrupted nodal ciliogenesis. [provided by MGI curators]
  • synonyms:
  • Fgfr1op N-terminal like,
  • 0610037P05Rik,
  • centrosomal protein 20,
  • Fopnl,
  • Cep20,
  • RIKEN cDNA 0610037P05 gene
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