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Allele : Alox5<tm1Fun> arachidonate 5-lipoxygenase; targeted mutation 1, Colin D Funk

Primary Identifier  MGI:1857125 Allele Type  Targeted
Attribute String  Null/knockout Gene  Alox5
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a neomycin resistance cassette into exon 6 disrupted the Alox5 gene. RT-PCR studies did not detect transcript in resident peritoneal macrophages of homozygous mutant mice. Western blot analysis of resident peritoneal macrophages of homozygous mutant mice did not detect ALOX5.
  • mutations:
  • Insertion
  • synonyms:
  • 5-LOX K/O,
  • 5-LOX K/O,
  • 5LO<->,
  • 5LX-,
  • 5-LO<->,
  • 5-LO<->,
  • 5-LO KO,
  • 5-LOX<->,
  • 5LX-,
  • 5-LOX<->,
  • 5-LO KO,
  • 5LO<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

135 Publication categories

Trail: Allele