| Primary Identifier | MGI:95606 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 14375 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables double-stranded DNA binding activity. Involved in positive regulation of lymphocyte differentiation. Acts upstream of or within DNA metabolic process; positive regulation of neurogenesis; and response to ionizing radiation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; early conceptus; gonad; and liver lobe. Orthologous to human XRCC6 (X-ray repair cross complementing 6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit neuron apoptosis, decreased body size, abnormal B and T cell morphology, increased incidence of tumorigenesis, and increased cellular sensitivity to irradiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
