| Type | MGI:General | Description | steady-state intracellular pH is lower than in wild-type mice in the absence of carbon dioxide and bicarbonate, the rate and extent of acidification on sodium removal and the rate of intracellular pH recovery on sodium re-addition is increased compared to in wild-type mice endothelial nitric oxide production is reduced compared with wild-type arteries arteries exhibit impaired resting and/or norepinephrine-induced nitric oxide production compared with wild-type arteries arteries exhibit reduced rho-kinase-dependent calcium sensitivity compared with wild-type arteries |
