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Publication : Telomeres and cancer: a tale with many endings.

First Author  Blasco MA Year  2003
Journal  Curr Opin Genet Dev Volume  13
Issue  1 Pages  70-6
PubMed ID  12573438 Mgi Jnum  J:82092
Mgi Id  MGI:2450826 Doi  10.1016/s0959-437x(02)00011-4
Citation  Blasco MA (2003) Telomeres and cancer: a tale with many endings. Curr Opin Genet Dev 13(1):70-6
abstractText  Telomerase activity is necessary to maintain the integrity of telomeres, which in turn prevent chromosome ends from being processed and signaled as damaged DNA. That cancer cells rely on telomerase to maintain functional telomeres and to divide indefinitely has highlighted the potential for developing novel therapeutic approaches that target telomerase.
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