Primary Identifier | MGI:6730127 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Irf3 |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct inserted an FRT-flanked neomycin resistance cassette with a 5' UTR upstream of exon 2 and an additional loxp site downstream of exon 2. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 2. |