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Protein Coding Gene : Tnrc6b trinucleotide repeat containing 6b

Primary Identifier  MGI:2443730 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  213988
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable RNA binding activity. Predicted to be involved in miRNA-mediated post-transcriptional gene silencing; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of with a positive effect on miRNA-mediated gene silencing by inhibition of translation. Predicted to act upstream of or within regulation of translation. Predicted to be located in cytosol. Predicted to be active in P-body and nucleoplasm. Is expressed in lung. Human ortholog(s) of this gene implicated in subserous uterine fibroid and uterine fibroid. Orthologous to human TNRC6B (trinucleotide repeat containing adaptor 6B).
PHENOTYPE: Mice homozygous for a gene trap allele exhibit neonatal and postnatal lethality with decreased body weight and infertility. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2700090M07 gene,
  • expressed sequence AI848765,
  • AI848765,
  • mKIAA1093,
  • 2700090M07Rik,
  • D230019K20Rik,
  • trinucleotide repeat containing 6b,
  • MGI:2146082,
  • Tnrc6b,
  • RIKEN cDNA D230019K20 gene,
  • A730065C02Rik,
  • RIKEN cDNA A730065C02 gene,
  • MGI:2442182,
  • MGI:1919875

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For