| Primary Identifier | MGI:2138162 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 98267 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in apoptotic process; intracellular signal transduction; and positive regulation of fibroblast apoptotic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in Flemming body; actin cytoskeleton; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including adrenal medulla; alimentary system; central nervous system; immune system; and testis. Orthologous to human STK17B (serine/threonine kinase 17b). PHENOTYPE: Homozygous null mice display abnormal T cell numbers, increased T cell proliferation, abnormal cytokine physiology, and decreased susceptibility to experimental autoimmune encephalomyelitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
