| Primary Identifier | MGI:1914702 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 67452 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables calcium-independent phospholipase A2 activity. Involved in cardiolipin metabolic process; regulation of cellular response to oxidative stress; and triglyceride homeostasis. Located in mitochondrion and peroxisome. Orthologous to human PNPLA8 (patatin like phospholipase domain containing 8). PHENOTYPE: Mice homozygous for a null allele exhibit some female-specific embryonic lethality, reduced body weight and temperature, cold intolerance, decreased exercise tolerance and decreased mitochondria function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
