| Primary Identifier | MGI:2148202 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 104158 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables carboxylesterase activity; sterol esterase activity; and triglyceride lipase activity. Involved in acylglycerol catabolic process. Acts upstream of or within several processes, including cellular lipid catabolic process; circadian temperature homeostasis; and cold-induced thermogenesis. Located in cytosol; endoplasmic reticulum lumen; and lipid droplet. Is expressed in several structures, including cochlear duct; gut; liver; nose; and respiratory system. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to human CES1 (carboxylesterase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased blood lipids, improved glucose tolerance, and increased energy expenditure. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
