Primary Identifier | MGI:5790794 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Cdkl5 |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to insert a FRT-flanked neomycin resistance (neo) cassette downstream of exon 5, and a single nucleotide change of C to T, leading to a nonsense mutation at arginine 59 (R59X). Flp-mediated recombination removed the neo cassette. |