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Allele : Tg(Myh6-Prkaa2*D157A)1Rti transgene insertion 1, Rong Tian

Primary Identifier  MGI:3639282 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh6-Prkaa2*D157A)1Rti
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene contains the full length cDNA of rat Prkaa2 with the aspartic acid at residue 157 changed to alanine to render the catalytic subunit inactive, tagged with an HA epitope, under the control of the cardiac specific mouse alpha-myosin heavy chain promoter. Prkaa2 activity is reduced in hearts at base line by 78%.
  • mutations:
  • Insertion
  • synonyms:
  • TG<alpha2DN>,
  • AMPK-DN,
  • TG<alpha2DN>,
  • AMPK-DN
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

17 Publication categories

Trail: Allele